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Aphidicolin

Antibiotic isolated from the fungus Nigrospora sphaerica, which is a potent antiviral and antimitotic agent; Inhibitor of DNA polymerase.

 


Chemical Name: : Aphidicolin
Molecular Weight: M.W.
338.48
Solubility: Soluble in DMSO.Preparation:
This product is soluble in DMSO (1 mg/ml),
Active Product:
Appearance: White to Off-White Powder

Storage: . Stable for 2 years as supplied by the manufacturer at (-20°C). DMSO solutions are stable for at least 6 months at -20°C.

 

 

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Comment

Structure    

 

Inhibits DNA replication at concentration ranging from 1-25 mg/ml.

 
 

 

 

Synonym: APC

Molecular Formula: C20H34O4

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  References

Yarbro, J.W., Mechanism of action of hydroxyurea. Semin. Oncol. 19, 1-10, (1992)